Bones of the vertebral column

8,128views

Bones of the vertebral column

year 1

year 1

Introduction to the immune system
Cytokines
Innate immune system
Complement system
T-cell development
B-cell development
MHC class I and MHC class II molecules
T-cell activation
B-cell activation, differentiation, and contraction
Cell-mediated immunity of CD4 cells
Cell-mediated immunity of natural killer and CD8 cells
Antibody classes
Somatic hypermutation and affinity maturation
VDJ rearrangement
Contracting the immune response and peripheral tolerance
B- and T-cell memory
Anergy, exhaustion, and clonal deletion
Vaccinations
Type I hypersensitivity
Type II hypersensitivity
Type III hypersensitivity
Type IV hypersensitivity
Sepsis
Neonatal sepsis
Abscesses
Food allergy
Anaphylaxis
Asthma
Immune thrombocytopenia
Autoimmune hemolytic anemia
Hemolytic disease of the newborn
Rheumatic heart disease
Myasthenia gravis
Graves disease
Pemphigus vulgaris
Serum sickness
Systemic lupus erythematosus
Poststreptococcal glomerulonephritis
Graft-versus-host disease
Contact dermatitis
X-linked agammaglobulinemia
Selective immunoglobulin A deficiency
Common variable immunodeficiency
IgG subclass deficiency
Hyperimmunoglobulin E syndrome
Isolated primary immunoglobulin M deficiency
Thymic aplasia
DiGeorge syndrome
Severe combined immunodeficiency
Adenosine deaminase deficiency
Ataxia-telangiectasia
Hyper IgM syndrome
Wiskott-Aldrich syndrome
Leukocyte adhesion deficiency
Chediak-Higashi syndrome
Chronic granulomatous disease
Complement deficiency
Hereditary angioedema
Asplenia
Thymoma
Ruptured spleen
Immunodeficiencies: T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Combined T-cell and B-cell disorders: Pathology review
Immunodeficiencies: Phagocyte and complement dysfunction: Pathology review
Glucocorticoids
Non-corticosteroid immunosuppressants and immunotherapies
Skin histology
Skin anatomy and physiology
Hair, skin and nails
Wound healing
Introduction to the skeletal system
Introduction to the muscular system
Bones of the neck
Anatomy clinical correlates: Bones, fascia and muscles of the neck
Bones of the vertebral column
Joints of the vertebral column
Vessels and nerves of the vertebral column
Muscles of the back
Anatomy of the suboccipital region
Anatomy clinical correlates: Bones, joints and muscles of the back
Anatomy of the muscles and nerves of the posterior abdominal wall
Bones of the upper limb
Fascia, vessels and nerves of the upper limb
Anatomy of the brachial plexus
Anatomy of the pectoral and scapular regions
Anatomy of the arm
Muscles of the forearm
Vessels and nerves of the forearm
Muscles of the hand
Anatomy of the sternoclavicular and acromioclavicular joints
Anatomy of the glenohumeral joint
Anatomy of the elbow joint
Anatomy of the radioulnar joints
Joints of the wrist and hand
Anatomy of the axilla
Anatomy clinical correlates: Clavicle and shoulder
Anatomy clinical correlates: Axilla
Anatomy clinical correlates: Arm, elbow and forearm
Anatomy clinical correlates: Wrist and hand
Anatomy clinical correlates: Median, ulnar and radial nerves
Bones of the lower limb
Fascia, vessels and nerves of the lower limb
Anatomy of the anterior and medial thigh
Muscles of the gluteal region and posterior thigh
Vessels and nerves of the gluteal region and posterior thigh
Anatomy of the popliteal fossa
Anatomy of the leg
Anatomy of the foot
Anatomy of the hip joint
Anatomy of the knee joint
Anatomy of the tibiofibular joints
Joints of the ankle and foot
Anatomy clinical correlates: Hip, gluteal region and thigh
Anatomy clinical correlates: Knee
Anatomy clinical correlates: Leg and ankle
Anatomy clinical correlates: Foot
Development of the axial skeleton
Development of the limbs
Development of the muscular system
Bone histology
Cartilage histology
Skeletal muscle histology
Skeletal system anatomy and physiology
Bone remodeling and repair
Cartilage structure and growth
Fibrous, cartilage, and synovial joints
Muscular system anatomy and physiology
Brachial plexus
Neuromuscular junction and motor unit
Sliding filament model of muscle contraction
Slow twitch and fast twitch muscle fibers
Muscle contraction
Muscle spindles and golgi tendon organs
Radial head subluxation (Nursemaid elbow)
Developmental dysplasia of the hip
Legg-Calve-Perthes disease
Slipped capital femoral epiphysis
Transient synovitis
Osgood-Schlatter disease (traction apophysitis)
Rotator cuff tear
Dislocated shoulder
Winged scapula
Thoracic outlet syndrome
Carpal tunnel syndrome
Ulnar claw
Erb-Duchenne palsy
Klumpke paralysis
Iliotibial band syndrome
Unhappy triad
Anterior cruciate ligament injury
Patellar tendon rupture
Meniscus tear
Patellofemoral pain syndrome
Sprained ankle
Achilles tendon rupture
Spondylolysis
Spondylolisthesis
Degenerative disc disease
Spinal disc herniation
Sciatica
Compartment syndrome
Rhabdomyolysis
Osteogenesis imperfecta
Craniosynostosis
Pectus excavatum
Arthrogryposis
Genu valgum
Genu varum
Pigeon toe
Flat feet
Club foot
Cleidocranial dysplasia
Achondroplasia
Osteomyelitis
Bone tumors
Osteochondroma
Chondrosarcoma
Osteoporosis
Osteomalacia and rickets
Osteopetrosis
Paget disease of bone
Osteosclerosis
Lordosis, kyphosis, and scoliosis
Osteoarthritis
Spondylosis
Spinal stenosis
Rheumatoid arthritis
Juvenile idiopathic arthritis
Gout
Calcium pyrophosphate deposition disease (pseudogout)
Psoriatic arthritis
Ankylosing spondylitis
Reactive arthritis
Spondylitis
Septic arthritis
Bursitis
Baker cyst
Muscular dystrophy
Polymyositis
Dermatomyositis
Inclusion body myopathy
Polymyalgia rheumatica
Fibromyalgia
Rhabdomyosarcoma
Lambert-Eaton myasthenic syndrome
Sjogren syndrome
Mixed connective tissue disease
Antiphospholipid syndrome
Raynaud phenomenon
Scleroderma
Back pain: Pathology review
Rheumatoid arthritis and osteoarthritis: Pathology review
Seronegative and septic arthritis: Pathology review
Gout and pseudogout: Pathology review
Systemic lupus erythematosus (SLE): Pathology review
Scleroderma: Pathology review
Sjogren syndrome: Pathology review
Bone disorders: Pathology review
Bone tumors: Pathology review
Myalgias and myositis: Pathology review
Neuromuscular junction disorders: Pathology review
Muscular dystrophies and mitochondrial myopathies: Pathology review
Pediatric musculoskeletal disorders: Pathology review
Acetaminophen (Paracetamol)
Non-steroidal anti-inflammatory drugs
Opioid agonists, mixed agonist-antagonists and partial agonists
Antigout medications
Osteoporosis medications
Fever of unknown origin: Clinical
Infective endocarditis: Clinical
Pneumonia: Clinical
Tuberculosis: Pathology review
Diarrhea: Clinical
Urinary tract infections: Clinical
Meningitis, encephalitis and brain abscesses: Clinical
Bites and stings: Clinical
Skin and soft tissue infections: Clinical
Protein synthesis inhibitors: Aminoglycosides
Antimetabolites: Sulfonamides and trimethoprim
Antituberculosis medications
Miscellaneous cell wall synthesis inhibitors
Protein synthesis inhibitors: Tetracyclines
Cell wall synthesis inhibitors: Penicillins
Miscellaneous protein synthesis inhibitors
Cell wall synthesis inhibitors: Cephalosporins
DNA synthesis inhibitors: Metronidazole
DNA synthesis inhibitors: Fluoroquinolones
Herpesvirus medications
Azoles
Echinocandins
Miscellaneous antifungal medications
Anthelmintic medications
Antimalarials
Anti-mite and louse medications
Joint pain: Clinical
Pediatric orthopedic conditions: Clinical
Rheumatoid arthritis: Clinical
Lower back pain: Clinical
Immunodeficiencies: Clinical
Fat-soluble vitamin deficiency and toxicity: Pathology review
Water-soluble vitamin deficiency and toxicity: B1-B7: Pathology review
Zinc deficiency and protein-energy malnutrition: Pathology review
Viral hepatitis: Clinical
HIV and AIDS: Pathology review
Integrase and entry inhibitors
Nucleoside reverse transcriptase inhibitors (NRTIs)
Protease inhibitors
Hepatitis medications
Non-nucleoside reverse transcriptase inhibitors (NNRTIs)
Neuraminidase inhibitors
Seronegative arthritis: Clinical
Systemic lupus erythematosus (SLE): Clinical
Sjogren syndrome: Clinical
Inflammatory myopathies: Clinical
Vasculitis: Clinical
Preoperative evaluation: Clinical
Postoperative evaluation: Clinical
General anesthetics
Local anesthetics
Neuromuscular blockers
Laxatives and cathartics
Anticoagulants: Heparin
Anticoagulants: Warfarin
Anticoagulants: Direct factor inhibitors
Antiplatelet medications
Insulins
Traumatic brain injury: Clinical
Neck trauma: Clinical
Chest trauma: Clinical
Abdominal trauma: Clinical
Anatomy of the vertebral canal
Anatomy of the descending spinal cord pathways
Anatomy of the ascending spinal cord pathways
Anatomy clinical correlates: Vertebral canal
Anatomy clinical correlates: Spinal cord pathways
Superficial structures of the neck: Posterior triangle
Superficial structures of the neck: Cervical plexus
Superficial structures of the neck: Anterior triangle
Deep structures of the neck: Prevertebral muscles
Anatomy of the thyroid and parathyroid glands
Anatomy of the larynx and trachea
Anatomy of the pharynx and esophagus
Anatomy of the lymphatics of the neck
Deep structures of the neck: Root of the neck
Fascia and spaces of the neck
Anatomy clinical correlates: Vessels, nerves and lymphatics of the neck
Anatomy clinical correlates: Viscera of the neck
Introduction to pharmacology
Enzyme function
Pharmacodynamics: Drug-receptor interactions
Pharmacodynamics: Agonist, partial agonist and antagonist
Pharmacodynamics: Desensitization and tolerance
Pharmacokinetics: Drug absorption and distribution
Pharmacokinetics: Drug metabolism
Pharmacokinetics: Drug elimination and clearance
Drug administration and dosing regimens
Mechanisms of antibiotic resistance

Notes

Bones of the Vertebral Column

Figure 1.  Section of the Spine
Figure 2. Features of a Typical Lumbar Vertebrae A. Superior View of Vertebra B. Lateral View of Vertebra
Figure 3. Lateral view of typical lumbar articulation.
Figure 4. Typical Cervical Vertebra. A. Lateral view of Cervical Vertebra B. Superior view of Cervical Vertebra
Figure 5. Atypical Cervical Vertebrae A. Superior view of C1 (Atlas) B. Posterosuperior view of C2 (Axis) C. Superior View of Vertebra Prominens (C7)
Figure 6. Typical Thoracic Vertebrae A. Lateral View of Articulating Thoracic Vertebrae B. Superior View of Thoracic Vertebra
Figure 7. Features of the Sacrum A. Anterior view B. Lateral view  C. Posterior view 
Figure 8. Sacral Crests, Posterior View

Transcript

Watch video only

The vertebral column, commonly referred to as the spine or spinal column, consists of 33 vertebrae organized in 5 main regions: 7 cervical, 12 thoracic, 5 lumbar, 5 sacral, and 4 coccygeal.

The vertebrae come in different shapes and sizes, and they have unique features depending on their region.

Typical vertebrae have a basic structure in common, consisting of a vertebral body, a vertebral arch, and 7 processes: a spinous process, 2 transverse processes, and 2 superior and 2 inferior articular processes.

The vertebral body is the thick, cylindrical, anterior portion of the vertebra, which functions in supporting weight.

As you move down the spine the vertebral bodies become larger, as they bear more weight.

Posterior to the vertebral body, there’s the vertebral arch, which consists of two pedicles and two laminae.

The pedicles are short, thick processes that project posteriorly from the vertebral body to meet the laminae, which are two broad, flat plates of bone, that unite in the midline and complete the vertebral arch.

The space between the walls of the vertebral arch and vertebral body is called the vertebral foramen.

And when you stack all the foramina on top of each other, that forms the vertebral, or spinal, canal, which forms a protective bony case around the spinal cord.

Focusing on the 7 processes of the vertebrae, first we have the spinous process, which extends posteriorly from the midline junction of the laminae and serves as an attachment site for ligaments and muscles.

Next, the left and right transverse processes, they extend posterolaterally from the junctions of the pedicles and laminae, while also serving as important attachment sites for ligaments and muscles.

Finally we have the four articular processes. First there’s the left and right superior articular processes, which project superiorly from the junctions of the pedicles and laminae.

Next are the left and right inferior articular processes, which project inferiorly from the junctions of the pedicles and laminae.

The superior articular processes, inferior articular processes, along with the pedicles, the vertebral bodies, and intervertebral discs between vertebral bodies, go on to create U shaped indentations called the superior and inferior vertebral notch.

So, let’s look at the articulation between two typical vertebrae from a lateral angle. The superior and inferior articular processes of each vertebra allow articulation with adjacent vertebrae via their articular facets.

The inferior articular process of the top vertebra comes into contact with the superior articular process of the bottom vertebra, forming a zygapophyseal joint, also called a facet joint.

The facet joints help keep the vertebrae properly aligned, while also allowing movement of the vertebral bodies. Furthermore, their orientation differs throughout the vertebral column.

This allows for different movements of the vertebral bodies in the cervical, thoracic, and lumbar regions.

While still looking from a lateral view, you can also see how the inferior vertebral notch of the vertebra on top aligns with the superior vertebral notch of the vertebra below it to form a canal called the intervertebral foramen, through which spinal nerves pass.

Okay, before moving on, let’s take a short break and see if you can recall the basic features of a typical vertebra. So now let’s look at the common features of typical vertebrae in each region.

Cervical vertebrae can be typical or atypical, and when it comes to the cervical column, the typical vertebrae are C3, C4, C5 and C6, while the atypical vertebrae are C1, C2 and C7.

The vertebral bodies of typical cervical vertebrae are smaller than the other regions, are wider from side to side, and have a concave superior surface and a convex inferior surface.

The lateral edges of the superior surface of the vertebral bodies are each called the uncus of the body, or the uncinate process.

Now, what really makes cervical vertebrae stand out is that they have a foramen transversarium, or transverse foramen, which is an opening on each of the transverse processes.

It's through these foramina that the vertebral arteries and corresponding veins pass.

The lateral ends of the transverse processes have two projections, an anterior tubercle and a posterior tubercle, which are attachment sites for the levator scapulae and scalene muscles.

The vertebral foramen of the cervical vertebrae is large and triangular shaped to accommodate the cervical enlargement of the spinal cord to fit through it.

The facets on cervical vertebrae are nearly horizontal and, as such, allow for the most movement of all the vertebral regions.

The superior articular facets are directed slightly supero-posteriorly, meaning the facets face up and back slightly, while the inferior articular facets are directed slightly inferiorly and anteriorly, meaning the facets face down and forward slightly.

This allows adjacent cervical vertebrae to sit nicely upon each other. The main movements the facet joints allow in the cervical region are: free flexion and extension, some lateral flexion, and limited rotation.

The spinous processes of the cervical vertebrae are short, where typically C2-C6 are bifid, meaning they have two protrusions at the posterior end that project posterolaterally.

But let’s not forget about the atypical cervical vertebrae! First, the C1 vertebra, also called the atlas, is a ring shaped bone that doesn’t have a body or a spinous process.

So, instead of a body, it has paired lateral masses that serve as a body and sustain the weight of the globe-like cranium just like Atlas of Greek mythology, who bore the weight of the literal world on his shoulders.

The transverse processes of the atlas arise from the lateral masses, so these processes are placed more laterally than those of the inferior vertebrae. This makes the atlas the widest of the cervical vertebrae.

Now, the lateral masses have two superior, concave, kidney-shaped articular surfaces.

These surfaces articulate with two large cranial protuberances on either side of the foramen magnum on the occipital bone, called the occipital condyles,to form the atlanto-occipital joint.

The anterior and posterior arches extend between the lateral masses and form a complete ring.

The anterior arch has an anterior tubercle and a facet for the dens, and the posterior arch has a posterior tubercle and a groove for the vertebral artery. On the anterior arch, there’s a tubercle for the transverse ligament.

The transverse ligament extends from one lateral mass to the other lateral mass on the atlas, passing between the spinal cord and the dens, which is a part of the C2 vertebra.

Speaking of which, the C2 vertebra is also called the axis, because it has a blunt tooth-like dens - or odontoid process.

The dens projects superiorly and articulates with the posterior surface of the anterior arch of the atlas, and it’s held in place by the transverse ligament.

Next, C2 also has two large, flat weight-bearing surfaces called the superior articular facets on which the atlas rotates.

It also has inferior articular processes, and transverse processes similar to the other cervical vertebrae.

Finally, C7, has a smaller transverse foramen than the other cervical vertebrae, and it is also called the vertebra prominens due to its long spinous process.

In most people it is the most prominent spinous process, and you can actually feel it if you run your finger and press along the midline of the back of your neck!

Okay. I prominens we’re done articulating the multi-faceted details of the cervical vertebrae for now.

Take a moment to see if you can recall the key structures of the typical and atypical cervical vertebrae.

All right! Next up are the thoracic vertebrae, which are located in the upper and middle back, between the cervical and lumbar vertebrae.

They are intermediate in size, though they do get bigger further down the vertebral column.

On quick glance, an easy way to identify the thoracic vertebrae is from a posterior lateral view, where they look like a giraffe!

This is compared to the lumbar vertebrae which we will talk about shortly, which look like a moose!

From a superior view, the typical thoracic vertebrae, which are T2 through T11, have a heart-shaped vertebral body, a vertebral foramen that is circular and small, and a pair of transverse processes that are long, strong, and extend posterolaterally. Let's look at a typical thoracic vertebra from a lateral view.

The facets of the superior articular processes are nearly vertical and face posteriorly and slightly laterally, while the facets of the inferior articular processes are also nearly vertical but face anteriorly and slightly medially,

Key Takeaways

The human vertebral column, also known as the spinal column or simply the spine, is a long, flexible structure made up of bones (vertebrae) separated by small cushions of intervertebral discs. It functions to protect the spinal cord, support the weight of the head, and allow movement of the trunk and limbs. The vertebral column is composed of 33 bones in total: 7 cervical (neck), 12 thoracic (chest), 5 lumbar (lower back), 5 sacral, and 4 coccygeal (fused into the coccyx). When viewed from the side, the spine has an S-shape. This is due to the inward curve of the cervical spine, and a gentle outward curve in the thoracic region. The lumbar spine slightly curves inward just like the cervical spine. All these curves help to distribute the weight of the head and body evenly and act as shock absorbers during movement.