Summary of Hyperplasia and hypertrophy
Questions on Hyperplasia and hypertrophy
A 39-year-old woman comes to the clinic with weight gain, facial swelling, and muscle weakness. Physical examination shows marked central obesity with thinning of the extremities and abundant purple striae covered the abdomen. Serum laboratory studies show glucose 205 mg/dL, cortisol 80 ug/dL and an elevated ACTH. ACTH levels are decreased after the administration of a high dose of dexamethasone. Which of the following is the most likely mechanism by which change occurred in this patient's adrenal glands?