Summary of Lac operon
The lac operon (lactose operon) is an operon required for the transport and metabolism of lactose in Escherichia coli and many other enteric bacteria. Although glucose is the preferred carbon source for most bacteria, the lac operon allows for the effective digestion of lactose when glucose is not available. Gene regulation of the lac operon was the first genetic regulatory mechanism to be understood clearly, so it has become a foremost example of prokaryotic gene regulation. It is often discussed in introductory molecular and cellular biology classes for this reason.
Flashcards on Lac operon
In the lac operon under conditions of low , adenylate cyclase activity generates cAMP from ATP, which activates catabolite activator protein (CAP), leading to increased transcription.