Osmosis video - PDE5 inhibitors

PDE5 (phosphodiesterase type 5) inhibitors are a class of drugs that are used to treat erectile dysfunction and pulmonary hypertension. These drugs work by inhibiting the activity of the enzyme phosphodiesterase type 5 (PDE5), which is responsible for breaking down cyclic guanosine monophosphate (cGMP) in the body. By inhibiting PDE5, these drugs increase the levels of cGMP, which relaxes the smooth muscle tissue in the blood vessels of the penis and lungs, leading to an increase in blood flow. Examples of PDE5 inhibitors include drugs like sildenafil, vardenafil, and tadalafil.