The diagnosis of molimina can be made by ruling out other possible causes for the symptoms. Thorough medical history, physical examination, diagnostic imaging, and laboratory tests can be performed at the discretion of the clinician in order to rule out depression, anxiety, anemia, leukemia, hypothyroidism, and other conditions that present with symptoms that may overlap with molimina.
Molimina typically resolves on its own, but several measures can help reduce symptom intensity. Lifestyle and dietary adjustments–such as increasing fruit and vegetable intake and reducing salt, sugar, fat, alcohol, and caffeine–may lessen symptoms; smoking cessation is also beneficial. Regular moderate exercise, adequate sleep, and effective stress-management strategies can improve mood stability and overall symptom control. Over-the-counter (OTC) analgesics, such as ibuprofen, can help relieve cramping and headaches. In individuals seeking stronger symptom relief, hormonal contraceptives that suppress ovulation, such as combined estrogen-progestin pills, may also be effective.