Today’s NCLEX-RN® question of the day focuses on an infant diagnosed with neuroblastoma, the nurse is reviewing the non-modifiable risk factors associated with the condition. Which risk factor should be included by the nurse? Can you figure it out?
The nurse is reviewing the non-modifiable risk factors for neuroblastoma with the parents of an infant recently diagnosed with this condition. Which risk factor should the nurse include?
A. Family history
B. Sex assigned at birth
C. Gestational age at birth
D. Ethnicity Scroll down for the correct answer!
The correct answer to today’s NCLEX-RN® Question is…
A. Family history
Rationale: Family history is a non-modifiable risk factor associated with the development of neuroblastoma.
Major Takeaway
The exact cause of neuroblastoma remains unknown; however, several non-modifiable risk factors have been recognized. These include a family history of neuroblastoma and genetic mutations in the MYCN oncogene, the ALK fusion oncogene, and mutations in tumor suppressor genes, like the PHOX2B gene.

Incorrect answer explanations
B. Sex assigned at birth
Rationale: Sex assigned at birth is not associated with the development of neuroblastoma.
C. Gestational age at birth
Rationale: The gestational age at birth is not associated with the development of neuroblastoma.
D. Ethnicity
Rationale: Ethnicity is not associated with the development of neuroblastoma.
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