Approach to trauma: Clinical sciences

Last updated: March 24, 2026

Approach to trauma: Clinical sciences

CCRN Prep Total

CCRN Prep Total

Anatomic and physiologic dead space
Ventilation
Ventilation-perfusion ratios and V/Q mismatch
Gas exchange in the lungs, blood and tissues
Approach to a cough (pediatrics): Clinical sciences
Reading a chest X-ray
Approach to respiratory distress (newborn): Clinical sciences
Approach to chest pain: Clinical sciences
Acute respiratory distress syndrome
Respiratory distress syndrome: Pathology review
Respiratory failure (pediatrics): Clinical sciences
Acute respiratory distress syndrome: Clinical sciences
Approach to postoperative respiratory distress: Clinical sciences
Approach to dyspnea: Clinical sciences
Upper respiratory tract infection
Apnea of prematurity
Approach to complications of prematurity (early): Clinical sciences
Apnea, hypoventilation and pulmonary hypertension: Pathology review
Hospital-acquired and ventilator-associated pneumonia: Clinical sciences
Acid-base map and compensatory mechanisms
Respiratory acidosis
Approach to respiratory alkalosis: Clinical sciences
Approach to lower airway obstruction (pediatrics): Clinical sciences
Approach to upper airway obstruction (pediatrics): Clinical sciences
Croup and epiglottitis: Clinical sciences
Croup
Pharyngitis, peritonsillar abscess, and retropharyngeal abscess (pediatrics): Clinical sciences
Asthma: Clinical sciences
Bronchodilators: Beta 2-agonists and muscarinic antagonists
Pneumonia: Pathology review
Pneumothorax
Pneumothorax: Clinical sciences
Pleural effusion, pneumothorax, hemothorax and atelectasis: Pathology review
Atelectasis: Clinical sciences
Approach to penetrating chest injury: Clinical sciences
Pulmonary embolism
Pulmonary embolism: Clinical sciences
Pulmonary shunts
Pulmonary hypertension
Pulmonary hypertension: Clinical sciences
Hypertension
Hypertensive emergency
Hypertension: Pathology review
Tracheoesophageal fistula
Esophageal atresia and tracheoesophageal fistula: Year of the Zebra
Bronchiolitis: Clinical sciences
Blood transfusion reactions and transplant rejection: Pathology review
Spinal fractures: Clinical sciences
Anatomy of the descending spinal cord pathways
Approach to differentiating lesions (spinal cord): Clinical sciences
Brain death: Clinical sciences
Pneumonia (pediatrics): Clinical sciences
Brain herniation
Pediatric brain tumors
Delirium
Delirium: Clinical sciences
Approach to encephalopathy (acute and subacute): Clinical sciences
Encephalitis
Approach to altered mental status: Clinical sciences
Approach to traumatic brain injury: Clinical sciences
Approach to traumatic brain injury (pediatrics): Clinical sciences
Traumatic brain injury: Pathology review
Epidural hematoma
Approach to trauma (pediatrics): Clinical sciences
Concussion and traumatic brain injury
Subarachnoid hemorrhage: Clinical sciences
Normal pressure hydrocephalus
Intracerebral hemorrhage
Approach to increased intracranial pressure: Clinical sciences
Subarachnoid hemorrhage
Neurogenic shock: Clinical sciences
Approach to shock (pediatrics): Clinical sciences
Shock: Pathology review
Shock
Approach to shock: Clinical sciences
Ischemic stroke
Acute stroke (ischemic or hemorrhagic) or TIA: Clinical sciences
Cerebral vascular disease: Pathology review
Arteriovenous malformation
Meningitis
Pelvic fractures: Clinical sciences
Subdural hematoma
Community-acquired pneumonia: Clinical sciences
Meningitis (pediatrics): Clinical sciences
Meningitis and brain abscess: Clinical sciences
Central nervous system infections: Pathology review
Syndrome of inappropriate antidiuretic hormone secretion: Clinical sciences
Approach to convulsive status epilepticus: Clinical sciences
Seizures and epilepsy
Approach to epilepsy: Clinical sciences
Approach to altered mental status (pediatrics): Clinical sciences
Nonbenzodiazepine anticonvulsants
Seizures: Pathology review
Spina bifida
Congenital neurological disorders: Pathology review
Electrolyte disturbances: Pathology review
Hyperosmolar hyperglycemic state: Clinical sciences
Compartment syndrome: Clinical sciences
Renal system anatomy and physiology
Intrinsic acute kidney injury (glomerular causes): Clinical sciences
Prerenal acute kidney injury: Clinical sciences
Prerenal azotemia
Intrinsic acute kidney injury (non-glomerular causes): Clinical sciences
Postrenal acute kidney injury: Clinical sciences
Approach to acute kidney injury: Clinical sciences
Approach to postoperative acute kidney injury: Clinical sciences
Renal failure: Pathology review
Chronic kidney disease
Chronic kidney disease: Clinical sciences
Nephrotic syndromes: Pathology review
Approach to hyperkalemia: Clinical sciences
Transplant rejection
Nephritic syndromes (pediatrics): Clinical sciences
The role of the kidney in acid-base balance
Urinary tract infections and kidney stones in pregnancy: Clinical sciences
Hemolytic-uremic syndrome
Approach to bleeding disorders (thrombocytopenia): Clinical sciences
Extrinsic hemolytic normocytic anemia: Pathology review
Thrombotic microangiopathy: Clinical sciences
Platelet disorders: Pathology review
Approach to blunt and penetrating abdominal injury: Clinical sciences
Approach to postoperative abdominal pain: Clinical sciences
Approach to acute abdominal pain (pediatrics): Clinical sciences
Non-accidental trauma and neglect (pediatrics): Clinical sciences
Small bowel ischemia and infarction
Bowel obstruction
Large bowel obstruction: Clinical sciences
Small bowel obstruction: Clinical sciences
Short bowel syndrome: Clinical sciences
Gastrointestinal bleeding: Pathology review
Hypovolemic shock: Clinical sciences
Congenital gastrointestinal disorders: Pathology review
Approach to bleeding disorders (platelet dysfunction): Clinical sciences
Cholestatic liver disease
Non-alcoholic fatty liver disease
Post-transplant lymphoproliferative disorders (NORD)
Transposition of the great vessels
Intussusception
Intussusception: Clinical sciences
Approach to the acute abdomen (pediatrics): Clinical sciences
Vasculitis: Pathology review
Necrotizing enterocolitis: Clinical sciences
Necrotizing enterocolitis: Year of the Zebra 2024
Guillain-Barré syndrome: Clinical sciences
Disseminated intravascular coagulation: Clinical sciences
Disseminated intravascular coagulation
Consumptive coagulopathy from massive transfusion: Clinical sciences
Sepsis: Clinical sciences
Approach to leukemia: Clinical sciences
Thrombosis syndromes (hypercoagulability): Pathology review
Malignant hyperthermia: Clinical sciences
Acute pancreatitis
Adrenal insufficiency: Pathology review
Deep vein thrombosis and pulmonary embolism: Pathology review
Immune thrombocytopenia
Immune thrombocytopenia: Clinical sciences
Hematopoietic medications
Glucocorticoids
Sickle cell disease: Clinical sciences
Anatomy clinical correlates: Spinal cord pathways
Acute coronary syndrome: Clinical sciences
Antidiuretic hormone
Diabetes insipidus and SIADH: Pathology review
Syndrome of inappropriate antidiuretic hormone secretion (SIADH)
Hyponatremia
Approach to hyponatremia: Clinical sciences
Approach to hyponatremia (pediatrics): Clinical sciences
Diabetes insipidus
Diabetes insipidus: Clinical sciences
Approach to hypoglycemia: Clinical sciences
Approach to hypoglycemia (pediatrics): Clinical sciences
Diabetic ketoacidosis: Clinical sciences
Diabetes mellitus (pediatrics): Clinical sciences
Diabetes mellitus: Pathology review
Pulmonary edema
Cerebral palsy
Hepatic encephalopathy: Clinical sciences
Approach to common musculoskeletal injuries (pediatrics): Clinical sciences
Approach to blunt chest injury: Clinical sciences
Pediatric musculoskeletal disorders: Pathology review
Approach to extremity injury: Clinical sciences
Neuroblastoma
Childhood and early-onset psychological disorders: Pathology review
Approach to trauma: Clinical sciences
Anatomy clinical correlates: Skull, face and scalp
Rhabdomyolysis
Compartment syndrome
Hypocalcemia
Hyperphosphatemia
Hyperkalemia
Sepsis (pediatrics): Clinical sciences
Sepsis
Neonatal sepsis
Empyema: Clinical sciences
Necrotizing soft tissue infections: Clinical sciences
Pressure-induced skin and soft tissue injury: Clinical sciences
Diffusion-limited and perfusion-limited gas exchange
Approach to acid-base disorders: Clinical sciences
Definitions of acids and bases
Acid-base disturbances: Pathology review
Catheter-associated urinary tract infection: Clinical sciences
Central line-associated bloodstream infection: Clinical sciences
Approach to medication exposure (pediatrics): Clinical sciences
Approach to household substance exposure (pediatrics): Clinical sciences
Approach to recreational substance exposure (pediatrics): Clinical sciences
Myocarditis: Clinical sciences
Pharmacodynamics: Drug-receptor interactions
Medication overdoses and toxicities: Pathology review
Opioid intoxication and overdose: Clinical sciences
Approach to stimulant use, intoxication, and overdose: Clinical sciences
Approach to hallucinogen, inhalant, and cannabis use, intoxication, and overdose: Clinical sciences
Cholinomimetics: Indirect agonists (anticholinesterases)
Suicide
Burns
Burns: Clinical sciences
Multiple organ dysfunction syndrome (MODS): Clinical sciences
Kawasaki disease
Approach to hypernatremia (pediatrics): Clinical sciences
Approach to a postoperative fever: Clinical sciences
Supraventricular arrhythmias: Pathology review
Aspiration pneumonia and pneumonitis: Clinical sciences
Cardiac preload
Cardiac cycle
Cardiac tumors
Cardiac work
Cardiac tamponade
Cardiac tamponade: Clinical sciences
Cardiac conduction velocity
Cardiac afterload
Cardiac contractility
ECG cardiac hypertrophy and enlargement
Ventricular tachycardia: Clinical sciences
Ventricular arrhythmias: Pathology review
ECG cardiac infarction and ischemia
Approach to tachycardia: Clinical sciences
Stroke volume, ejection fraction, and cardiac output
Dilated cardiomyopathy
Supraventricular tachycardia: Clinical sciences
Class IV antiarrhythmics: Calcium channel blockers and others
Atrial fibrillation and atrial flutter: Clinical sciences
Positive inotropic medications
Class I antiarrhythmics: Sodium channel blockers
Cardiomyopathies: Pathology review
Class III antiarrhythmics: Potassium channel blockers
Hypertrophic cardiomyopathy
Ventricular fibrillation
Aortic stenosis: Clinical sciences
Myocarditis
Brief, resolved, unexplained event (BRUE): Clinical sciences
Mitral stenosis: Clinical sciences
Congestive heart failure: Clinical sciences
Atrial flutter
Pressures in the cardiovascular system
Cardiovascular system anatomy and physiology
Restrictive cardiomyopathy
Airflow, pressure, and resistance
Total anomalous pulmonary venous return
Atrial fibrillation
Hypertrophic cardiomyopathy: Clinical sciences
Hypothermia: Clinical sciences
Hemothorax: Clinical sciences
Anaphylaxis: Clinical sciences
Abdominal aortic aneurysm: Clinical sciences
Muscarinic antagonists
Selective serotonin reuptake inhibitors
General anesthetics
Neuromuscular blockers
Right heart failure: Clinical sciences
Heart failure: Pathology review
Mitral valve disease
Approach to a murmur (pediatrics): Clinical sciences
Tricuspid valve disease
ACE inhibitors, ARBs and direct renin inhibitors
Patent ductus arteriosus
Adrenergic antagonists: Beta blockers
Pheochromocytoma
cGMP mediated smooth muscle vasodilators
Cardiac conduction system
Hypoplastic left heart syndrome
Hypoplastic left heart syndrome: Year of the Zebra 2024
Heart blocks: Pathology review
Rheumatic heart disease
Abnormal heart sounds
Valvular heart disease: Pathology review
Coronary artery disease: Pathology review
Pericarditis: Clinical sciences
Approach to hypertension: Clinical sciences
Deep vein thrombosis
Deep vein thrombosis: Clinical sciences
Approach to a fever: Clinical sciences
Anticoagulants: Heparin
Approach to hypercoagulable disorders: Clinical sciences
Heparin-induced thrombocytopenia
Thrombolytics
Atrial septal defect
Superior vena cava syndrome
Introduction to the somatic and autonomic nervous systems
Anticonvulsants and anxiolytics: Benzodiazepines
Anticonvulsants and anxiolytics: Barbiturates
Approach to congenital heart diseases (acyanotic): Clinical sciences
Tetralogy of Fallot
Cyanotic congenital heart defects: Pathology review
Approach to congenital heart diseases (cyanotic): Clinical sciences
Ventricular septal defect
Aortic valve disease
Pyloric stenosis
Aortic dissection
Pneumonia
Aortic dissection: Clinical sciences
Aortic dissections and aneurysms: Pathology review
Coarctation of the aorta
Acyanotic congenital heart defects: Pathology review
Pulmonary valve disease
Pulmonary chemoreceptors and mechanoreceptors
Zones of pulmonary blood flow
Carotid artery stenosis screening: Clinical sciences
Endocarditis
Endocarditis: Pathology review
Valvular insufficiency (regurgitation): Clinical sciences
Infectious endocarditis: Clinical sciences
Choanal atresia
Tetralogy of Fallot: Year of the Zebra
Mycoplasma pneumoniae
Measles virus
Respiratory alkalosis
Metabolic alkalosis
Approach to metabolic alkalosis: Clinical sciences
Approach to respiratory acidosis: Clinical sciences
Metabolic acidosis
Approach to metabolic acidosis: Clinical sciences
Pericardial disease: Pathology review
Atherosclerosis and arteriosclerosis: Pathology review
Cardiac and vascular tumors: Pathology review
Peripheral artery disease: Pathology review

Decision-Making Tree

Transcript

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Trauma is one of the major causes of mortality and morbidity worldwide. A standardized approach to trauma, known as the “trauma protocol” allows providers to systematically assess and quickly identify potentially life-threatening injuries, while simultaneously initiating resuscitation. The trauma protocol is composed of primary, secondary, and tertiary surveys, performed one after another. The goal is to first identify life-threatening injuries and stabilize the patient; then, perform a more thorough head-to-toe assessment to catch the not-so-obvious injuries; and finally, follow up 24 hours later to make sure no other injuries were missed. This protocol is performed on every trauma patient regardless of the mechanism of injury.

So, when a patient presents with trauma, start with a primary survey. which can be summarized as A, B, C, D, and E.

A stands for Airway. Ensure your patient has an open airway and the ability to maintain a patent airway. Start by asking them their name and what happened. If they can speak, they have an open airway. However, if they show any signs of airway compromise, such as altered mental status, gurgling noises, inability to speak clearly, or evidence of an expanding neck hematoma, secure the airway as soon as possible. In this case, intubate or consider obtaining a surgical airway via cricothyroidotomy. Also, stabilize the C-spine to maintain cervical spine restriction by placing a cervical collar and keeping it in place until a traumatic injury to this area has been ruled out.

The next step in the primary survey is B for Breathing. This part focuses on identifying any injuries that affect ventilation and oxygenation. Key assessments include checking for tracheal deviation; evaluating for symmetrical chest rise; auscultating for lung sounds; and palpating the chest wall for evidence of trauma. Any injuries that can impair ventilation such as pneumothorax or hemothorax should be addressed immediately with bedside procedures such as rapid needle decompression with subsequent chest tube placement, needle thoracocentesis, or tube thoracostomy. Also remember to place supplemental oxygen on all adult trauma patients, and monitor oxygen saturation with pulse oximetry.

Okay, let’s move on to C for Circulation. Hypotension in an adult trauma patient is assumed to be from bleeding until proven otherwise, so look for any signs of external or internal bleeding. Additionally, place two large-bore intravenous or intraosseous catheters for fluid resuscitation and transfusion of blood products. Be sure to place them away from the area of the trauma in case there’s a major vascular injury. Finally monitor their hemodynamic status by observing their level of consciousness, skin perfusion, and vital signs.

Now, here’s a clinical pearl! The chest, abdomen, retroperitoneum, and long bones like the femur, are areas that can accommodate large amounts of blood if an internal hemorrhage is present. If you suspect injuries to these areas, keep a close eye on your patient's blood pressure and heart rate, since hemorrhagic shock can occur very quickly.

Next up is D for Disability, focusing on neurological status assessment. Assess your patient’s level of consciousness by calculating the Glasgow Coma Scale, or GCS. Also check pupillary size and reaction to light, and look for signs of spinal cord injury by assessing motor function and sensation in all four extremities.

Here's another clinical pearl! The GCS is a scoring tool used to assess a patient's neurological condition. It evaluates eye opening, verbal response, and motor response. Eye opening can be assessed as spontaneous, 4 points; to verbal stimuli, 3 points; only to pain stimuli, 2 points; or no response, 1 point. You can remember this by SEES: 4 letters for 4 eye points! Similarly, verbal response is evaluated as oriented and coherent, 5 points; confused or inappropriate words, 4 points; incomprehensible sounds, 3 points; verbal response to pain, 2 points; no verbal response, 1 point. Remember this by TALKS: 5 letters for 5 verbal points! Lastly, motor response has 6 categories: obeys commands, 6 points; localizing to pain, 5 points; withdraws to pain, 4 points; flexion to pain, also known as decorticate posturing, 3 points; extension response to pain, or decerebrate posturing, 2 points; and no response, 1 point. Remember this by MOVING: 6 letters for 6 points! Now, the score can range from 15, indicative of a normal functioning patient, to 3, which is indicative of a comatose patient. Any patient with a GCS of 8 or less needs to be intubated. Remember, GCS of 8, intubate!

Lastly, let’s discuss E for Exposure and Environmental control. Remove all of your patient’s clothing for a thorough assessment and to eliminate any potential contamination. Remember to place warm blankets on your patient to prevent hypothermia.

Alright, now that the primary survey is completed and your patient has been stabilized, let’s discuss the secondary survey. This involves a thorough history and physical examination and additional work-up to identify any underlying traumatic injuries that were not obvious during the primary survey.

Now, essential components of your patient’s history include known allergies, current medications, past illness, pregnancy status, timing of their most recent oral intake, and events related to the injury. The physical exam should follow a head-to-toe sequence, and includes obtaining labs and imaging to assist in identifying underlying traumatic injuries. Keep in mind that primary and secondary surveys are not like your typical ABCDE and H&P. They need to be done fast, as there is no time to waste in trauma. Primary survey typically takes 1-2 minutes, and H&P portion of the secondary survey usually takes about 5 minutes. Typical labs include a type and cross, CBC, and CMP.

Additional tests to consider are ABGs; coagulation studies including a rotational thermoelectrometry, also known as ROTEM; lipase, and serum alcohol level. Also, order urine studies like urinalysis; urine pregnancy test for biological female patients; and urine toxicology screen.

Sources

  1. "ACS/ASE Medical Student Core Curriculum Trauma I - ABCs of Trauma.” 2022, " facs.org