Summary of Microtubule inhibitors
Vincristine is a chemotherapy medication used to treat a number of types of cancer. This includes acute lymphocytic leukemia, acute myeloid leukemia, Hodgkin's disease, neuroblastoma, and small cell lung cancer among others. Vincristine works partly by binding to the beta-tubulin protein, stopping the cell from separating its chromosomes during the metaphase; the cell then undergoes apoptosis.
Flashcards on Microtubule inhibitors
are two microtubule inhibiting antineoplastic medications that bind to and inhibit β-tubulin, thereby inhibiting microtubule polymerization and mitotic spindle formation.