Megaloblastic anemia
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Megaloblastic anemia
SBL Exam 1
SBL Exam 1
Glucose-6-phosphate dehydrogenase (G6PD) deficiency
Anemia of chronic disease
Alpha-thalassemia
Beta-thalassemia
Iron deficiency anemia
Autoimmune hemolytic anemia
Paroxysmal nocturnal hemoglobinuria
Hereditary spherocytosis
Sickle cell disease (NORD)
Fanconi anemia
Megaloblastic anemia
Folate (Vitamin B9) deficiency
Vitamin B12 deficiency
Diamond-Blackfan anemia
Hemophilia
Thrombotic thrombocytopenic purpura
Hemolytic-uremic syndrome
Von Willebrand disease
Disseminated intravascular coagulation
Hodgkin lymphoma
Non-Hodgkin lymphoma
Chronic leukemia
Acute leukemia
Myelodysplastic syndromes
Langerhans cell histiocytosis
Multiple myeloma
Monoclonal gammopathy of undetermined significance
Waldenstrom macroglobulinemia
Microcytic anemia: Pathology review
Non-hemolytic normocytic anemia: Pathology review
Plasma cell disorders: Pathology review
Leukemias: Pathology review
Lymphomas: Pathology review
Myeloproliferative disorders: Pathology review
Key Takeaways
Megaloblastic anemia is a type of anemia caused by deficiencies in folic acid (folate) or vitamin B12. Folic acid and vitamin B12 are essential for DNA synthesis, and thus the production of healthy red blood cells. Megaloblastic anemia is characterized by large, nucleated red blood cell precursors which don't divide and produce more red blood cells as normal precursor cells do. Symptoms include fatigue, shortness of breath, and pale skin.