Assessment of Renal tubular defects: Pathology review: Video | Osmosis

Question

A 58-year-old woman comes to the clinic complaining of headaches, palpitations, and muscle pain for the last 2 months. The patient’s medical history is non-contributory, and she is not currently taking any medications. The patient’s temperature is 37°C (98.6°F), pulse is 80/min, respirations are 16/min, and blood pressure is 186/92 mmHg. The physician prescribes lisinopril 10 mg and recommends a follow up in one month. One month later, the patient returns to the clinic with persistent symptoms. Upon further questioning, the patient admits to consumption of five cups of Egpytian licorice tea daily for the past six months. Laboratory tests are obtained, and the results are shown below:

Laboratory value	Result
Blood, serum, plasma
Potassium	3.2 mEq/L
Bicarbonate	44 mEq/L
Aldosterone	decreased
Renin	decreased

Which of the following enzymes is most likely inhibited in this patient?

Accepted Answer

11&#946;-hydroxysteroid dehydrogenase

Answer

17&#945;-hydroxylase

Answer

21-hydroxylase

Answer

11&#946;-hydroxylase

Answer

5&#945;-reductase

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Renal tubular defects: Pathology review

Pathology

Renal system