Reviewed by Rishi Desai, MD, MPH
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Proximal convoluted tubule
The proximal convoluted tubule is responsible for the most amount reabsorption of almost all filtered substances (sodium, glucose, amino acids, etc) and reabsorbs around 67% of each filtered substance. Reabsorption of sodium and water here is isotonic; remaining sodium in the tubule affects the glomerulotubular balance and would decrease glomerular filtration rate if in excess. 
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Proximal convoluted tubule
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