Approach to acute pelvic pain (GYN): Clinical sciences
Introduction 0:00–0:55
Acute pelvic pain is defined as pain that arises from the pelvic organs and structures and has been present for less than 3 months.
It’s a common gynecologic problem that may require urgent evaluation and treatment, as in cases of ruptured ectopic pregnancy or adnexal torsion.
Other, usually less urgent, gynecologic causes of acute pelvic pain include early pregnancy loss, primary dysmenorrhea, endometriosis, adnexal masses, and pelvic inflammatory disease.
Acute pelvic pain also can be secondary to intimate partner violence or assault. Finally, it may arise from non-gynecologic sources, such as the gastrointestinal tract, urinary tract, or musculoskeletal system.When assessing a patient with acute pelvic pain, the first step is to assess their CABCDE to determine if they’re stable or unstable.
Unstable 0:55–1:28
If the patient is unstable, control hemorrhage; stabilize airway, breathing, and circulation; obtain IV access; and monitor vital signs.
Then, perform a focused history and physical exam, obtain an hCG to assess for pregnancy, and get a pelvic ultrasound. A rapid bedside ultrasound might be necessary to avoid a delay in treatment.Now, if the hCG test is positive, consider an ectopic pregnancy.
Ruptured ectopic pregnancy 1:28–2:01
The history may reveal syncope and vaginal bleeding, and physical exam might be positive for hypotension and tachycardia, as well as abdominal tenderness with rebound pain or guarding.
If the ultrasound indicates an absence of an intrauterine pregnancy and possible free fluid or adnexal mass, consider a ruptured ectopic pregnancy.
Proceed with an operative laparoscopy to confirm your diagnosis and stabilize the patient.Alright, if the hCG test is negative, consider another gynecologic emergency, adnexal torsion, although keep in mind this may also occur during pregnancy.
Adnexal torsion 2:01–3:10
This is most commonly due to the presence of an ovarian cyst, and occurs when an enlarged adnexa, consisting of the ovary, fallopian tube, and supporting ligaments, twists upon itself and stops blood flow to the ovary and tube.
The patient may report sudden onset of pelvic or abdominal pain, fever, nausea, and vomiting. Physical examination will demonstrate abdominal tenderness with rebound pain or guarding, and possibly a pelvic mass.The ultrasound will show an enlarged adnexa, typically larger than 5 centimeters in size, and may demonstrate absent Doppler flow in the ovarian vessels, as well as the whirlpool sign that reflects the twisted arterial and venous flow representing the twisted pedicle of the adnexa.
These findings are consistent with adnexal torsion. Proceed with an operative laparoscopy for diagnosis and rapid intervention in order to preserve ovarian function and fertility.Now that we discussed the unstable patient, let’s talk about stable ones.
Stable patient3:10–3:31
The first step here is to perform a focused history and physical exam, and obtain an hCG to assess for pregnancy. If hCG is positive, evaluate for causes of acute pain that are related to pregnancy.Let’s start with ectopic pregnancy.
Ectopic pregnancy 3:31–4:45
The history usually reveals unilateral pelvic pain, and possibly vaginal bleeding. The patient may report a history suggestive of fallopian tube injury, such as prior pelvic inflammatory disease, tubal surgery, or ectopic pregnancy.
Physical exam may reveal abdominal or pelvic tenderness, or an adnexal mass with tenderness. If you see this, consider an ectopic pregnancy and obtain a quantitative hCG and a pelvic ultrasound.
If the hCG is greater than 3,500 and the ultrasound demonstrates no evidence of an intrauterine pregnancy, with or without an adnexal mass, the diagnosis is ectopic pregnancy.Here’s a high-yield fact!
If the hCG is 3,500 or more, the ultrasound should reveal evidence of an intrauterine pregnancy. At that hCG level, the absence of intrauterine findings is diagnostic of an ectopic pregnancy.
However, if the hCG is less than 3,500, you might be dealing with a miscarriage or even a normal early pregnancy, so be sure to follow the patient closely with serial hCG levels and ultrasounds.Next, consider early pregnancy loss.
Early pregnancy loss4:45–5:32
In this case, the patient is more likely to report midline pelvic pain and possibly cramping and vaginal bleeding. The physical exam may or may not reveal an open cervical os with bleeding and passage of tissue.
Consider an early pregnancy loss and obtain a pelvic ultrasound. If it shows evidence of a nonviable intrauterine pregnancy, the diagnosis is early pregnancy loss.Here’s a clinical pearl!
A nonviable pregnancy can appear on ultrasound in a variety of ways, such as having a crown-rump length of 7 mm or greater with no cardiac activity, or a mean gestational sac diameter measuring 25 mm with no embryo.
Now that we discussed acute pelvic pain in pregnancy, let’s move on to patients with a negative hCG test, starting with primary dysmenorrhea.
Primary dysmenorrhea 5:32–6:40
These patients report cyclic pelvic pain that began 6 to 12 months after menarche and may also experience cyclic nausea, vomiting, diarrhea, headaches, and muscle cramps.
The cyclic nature of the symptoms and the absence of pelvic pathology is the key to the diagnosis of primary dysmenorrhea.Here’s another clinical pearl!
A pelvic exam is not necessary for the diagnosis of primary dysmenorrhea, especially when the patient is an adolescent. In these cases, you can start with a trial of medical management for 3 to 6 months; if symptoms don’t resolve, proceed with a pelvic exam and consider a pelvic ultrasound to evaluate for pelvic pathology as a cause of their dysmenorrhea.
Let’s move on to endometriosis. History may include the 4 “Ds”: dysmenorrhea, dyspareunia, dyschezia, and dysuria.
Endometriosis6:40–7:42
These symptoms, as well as generalized pelvic pain, might be cyclic in nature or exacerbated by menses. Physical exam may reveal abdominal or pelvic tenderness and can be positive for an abdominal or pelvic mass, reduced uterine mobility, a tender posterior vaginal fornix, or rectovaginal nodularity.
If this is the case, think about endometriosis, obtain a pelvic ultrasound, and perhaps perform a diagnostic laparoscopy to confirm your diagnosis.
The ultrasound may reveal an endometrioma, while laparoscopy may also show an endometrioma or endometriotic implants and scarring.
Keep in mind that some clinicians choose to make a presumptive diagnosis of endometriosis, using history and physical exam alone, since surgery involves greater risks and cost to the patient.Now let’s consider adnexal masses.
The history might reveal intermittent unilateral pain, abdominal distention, and pelvic pressure; while the physical exam might show abdominal or adnexal tenderness or adnexal fullness.
Benign or malignant adnexal mass 7:42–9:11
In this case, consider an adnexal mass and obtain a pelvic ultrasound. If the ultrasound demonstrates a cystic or solid adnexal mass, you have the diagnosis of a benign or malignant adnexal mass.
Here’s a clinical pearl! The diagnosis and management of adnexal masses is complicated and is determined by multiple factors, including patient history, risk factors for malignancy, and ultrasound findings.
The differential diagnosis includes a simple ovarian cyst, endometrioma, cystadenoma, teratoma, hydrosalpinx, tubo-ovarian abscess, an adnexal leiomyoma, or malignancy.
Surgical evaluation is indicated for those with significant pain, or when there’s a complex mass suspicious for malignancy.
Additionally, a common cause of acute pelvic pain is a ruptured ovarian cyst. This often happens when a functional ovarian cyst develops after ovulation, and the contents spill into the abdomen and irritate the peritoneum.
The patient will report a sudden episode of pain when the cyst ruptures, but the pain gradually improves over several days.Alright, let’s talk about pelvic inflammatory disease.
Pelvic inflammatory disease9:11–10:15
History reveals recent sexual intercourse and intermenstrual bleeding. It may also reveal pelvic or abdominal pain, vaginal discharge or fever.
The physical exam might show mucopurulent cervical discharge. If the examination reveals one or more of the following: pelvic tenderness, abdominal tenderness, or cervical motion tenderness, you can make a clinical diagnosis of pelvic inflammatory disease.
Keep in mind that you may increase the diagnostic specificity with ancillary findings like elevated white blood cell count, or positive test for cervical infection, but you only need the clinical findings to actually make the diagnosis.Here’s a final high-yield fact!
Pelvic inflammatory disease is commonly caused by sexually transmitted organisms, such as gonorrhea, chlamydia, and mycoplasma, but can also be caused by organisms normally found in the vaginal flora.
Finally, consider intimate partner violence or assault. The patient may report a history of physical or sexual violence; psychological or verbal abuse; or symptoms of depression or anxiety.
Intimate partner violence or assault10:15–10:58
Patients may not be forthcoming with a history of assault or violence. Confidentiality and sensitivity are essential when discussing assault or abuse, and it’s important to ask partners or caregivers for privacy during these discussions.After considering and assessing for gynecologic causes of acute pelvic pain, consider and assess for alternative diagnoses.
Other possible causes 10:58–11:18
These include appendicitis, diverticulitis, small bowel obstruction, urinary tract infection, interstitial cystitis, nephrolithiasis, and musculoskeletal conditions.
Alright, as a quick recap… Emergent causes of acute pelvic pain include ruptured ectopic pregnancy and adnexal torsion. Other gynecologic causes of acute pelvic pain are early pregnancy loss, primary dysmenorrhea, endometriosis, adnexal masses, and pelvic inflammatory disease.
Review11:18–11:43
Finally, intimate partner violence or assault can also lead to acute pelvic pain.
- "ACOG Practice Bulletin no.193: Tubal Ectopic Pregnancy" Obstet Gynecol (2018)
- "ACOG Committee Opinion no. 518: Intimate Partner Violence" Obstet Gynecol (2012)
- "ACOG Committee Opinion no. 783: Adnexal Torsion in Adolescents" Obstet Gynecol (2019)
- "ACOG Committee Opinion no. 760: Dysmenorrhea and Endometriosis in the Adolescent" Obstet Gynecol (2018)
- "ACOG Practice Bulletin no. 200: Early Pregnancy Loss" Obstet Gynecol (2018)
- "ACOG Committee Opinion no. 777: Sexual Assault" Obstet Gynecol (2019)
- "Characteristics and Management of Ovarian Torsion in Premenarchal Compared With Postmenarchal Patients" Obstet Gynecol (2015)
- "Primary dysmenorrhea: advances in pathogenesis and management" Obstet Gynecol (2006)
- "Management of the adnexal mass" Obstet Gynecol (2011)
- "Intimate Partner Violence and Women's Health" Obstet Gynecol (2019)
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