Miscarriage, also known as spontaneous abortion and pregnancy loss, is the natural death of an embryo or fetus before it is able to survive independently. Some use the cutoff of 20 weeks of gestation after which fetal death is known as a stillbirth. The most common symptoms of a miscarriage is vaginal bleeding. This may occur with or without pain. Tissue or clot like material may also come out the vagina. Sadness, anxiety, and guilt may also occur. There are many causes of miscarriage from chromosomal abnormalities to drug induced toxicity and infection.