Restless legs syndrome

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Restless legs syndrome

Nervous system and special senses

Adverse effects of drugs on the nervous system

Global cerebral dysfunction

Metabolic disorders

Neurologic pain syndromes

Key Takeaways

Restless legs syndrome, also known as Willis-Ekbom disease, is a neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations. It is often bilateral and most commonly affects the legs, but can affect the arms, torso, head, and even phantom limbs. Moving the affected body part modulates the sensations, providing temporary relief. The exact cause of RLS is not known, but it is believed to be related to a dysfunction of the brain's dopamine system. RLS can be treated with medications like dopamine agonists and benzodiazepines; and lifestyle changes, such as avoiding aggravating factors like caffeine intake.