Serotonin syndrome
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Serotonin syndrome
Nervous system and special senses
Adverse effects of drugs on the nervous system
Cerebrovascular disease
Congenital disorders
Cranial and peripheral nerve disorders
Degenerative disorders or amnesic syndromes
Demyelinating disorders
Disorders relating to the spine, spinal cord, and spinal nerve roots
Global cerebral dysfunction
Infectious, immunologic, and inflammatory disorders
Metabolic disorders
Movement disorders
Neurologic pain syndromes
Neuromuscular disorders
Paroxysmal disorders
Sleep disorders
Traumatic and mechanical disorders and disorders of increased intracranial pressure
Disorders of the ear
Disorders of the eye and eyelid
Nervous system and special senses pathology review
Key Takeaways
Serotonin syndrome is a potentially life-threatening condition that occurs when there is an excess of serotonin, a neurotransmitter in the brain, leading to a dangerous increase in nerve cell activity. Serotonin syndrome can occur as a result of taking certain medications, including selective serotonin reuptake inhibitors (SSRIs), monoamine oxidase inhibitors (MAOIs), and serotonin-norepinephrine reuptake inhibitors (SNRIs) or taking a combination of medications that increase serotonin levels. Symptoms include agitation, confusion, muscle rigidity and hyperreflexia, hypertension, dysrhythmias, diaphoresis, and tachypnea. Treatment may include discontinuing the culprit drug, supportive management, and providing cyproheptadine.