Transcription of DNA
Translation of mRNA
Amino acids and protein folding
Protein structure and synthesis
DNA damage and repair
Mitosis and meiosis
Adenosine deaminase deficiency
Acute radiation syndrome
Purine and pyrimidine synthesis and metabolism disorders: Pathology review
0 / 6 complete
Xeroderma pigmentosum (XP) is a rare autosomal recessive genetic disorder that affects the body's ability to repair damage to DNA caused by ultraviolet (UV) radiation. Individuals with XP are extremely sensitive to UV radiation and are at a high risk for developing skin cancers like basal cell carcinoma, squamous cell carcinoma, and melanoma. They may also develop eye problems, including photophobia, conjunctivitis, and corneal ulcers. Symptoms of XP can include dry, scaly, and pigmented skin, and uneven pigmentation. In severe cases, neurological symptoms such as developmental delay, progressive hearing loss, and cognitive impairment can also occur. Treatment primarily focuses on preventing(avoiding exposure to UV radiation by staying indoors, wearing protective clothing and sunscreen, and using protective eyewear) and managing symptoms.
Copyright © 2023 Elsevier, except certain content provided by third parties
Cookies are used by this site.
USMLE® is a joint program of the Federation of State Medical Boards (FSMB) and the National Board of Medical Examiners (NBME). COMLEX-USA® is a registered trademark of The National Board of Osteopathic Medical Examiners, Inc. NCLEX-RN® is a registered trademark of the National Council of State Boards of Nursing, Inc. Test names and other trademarks are the property of the respective trademark holders. None of the trademark holders are endorsed by nor affiliated with Osmosis or this website.