Neuroleptic malignant syndrome
Neuroleptic malignant syndrome
Pathophysiology
Biliary disorders
Colorectal disorders
Anal fissure
Anal fistula
Hemorrhoid
Rectal prolapse
Diverticulosis and diverticulitis
Crohn disease
Microscopic colitis
Ulcerative colitis
Irritable bowel syndrome
Ischemic colitis
Small bowel ischemia and infarction
Bowel obstruction
Gallstone ileus
Intestinal adhesions
Volvulus
Colorectal polyps
Familial adenomatous polyposis
Gardner syndrome
Juvenile polyposis syndrome
Peutz-Jeghers syndrome
Esophageal disorders
Food allergies and food sensitivities
Gastric disorders
Hepatic disorders
Alcohol-associated liver disease
Alpha 1-antitrypsin deficiency
Autoimmune hepatitis
Benign liver tumors
Budd-Chiari syndrome
Cholestatic liver disease
Cirrhosis
Hemochromatosis
Hepatic encephalopathy
Viral hepatitis
Hepatitis A and Hepatitis E virus
Hepatitis B and Hepatitis D virus
Hepatitis C virus
Jaundice
Neonatal hepatitis
Non-alcoholic fatty liver disease
Portal hypertension
Reye syndrome
Wilson disease
Infectious diarrhea
Adenovirus
Bacillus cereus (Food poisoning)
Campylobacter jejuni
Clostridium difficile (Pseudomembranous colitis)
Clostridium perfringens
Cryptosporidium
Cytomegalovirus
Entamoeba histolytica (Amebiasis)
Escherichia coli
Giardia lamblia
Norovirus
Rotavirus
Salmonella (non-typhoidal)
Shigella
Staphylococcus aureus
Vibrio cholerae (Cholera)
Yersinia enterocolitica
Ingestion of toxic substances or foreign bodies
Metabolic disorders
Neoplasms
Nutrition and vitamin disorders
Pancreatic disorders
Peritoneum and peritoneal cavity disorders
Small intestine disorders
Gastrointestinal system/Nutrition pathology review
Appendicitis: Pathology review
Cirrhosis: Pathology review
Colorectal polyps and cancer: Pathology review
Congenital gastrointestinal disorders: Pathology review
Disorders of amino acid metabolism: Pathology review
Disorders of carbohydrate metabolism: Pathology review
Diverticular disease: Pathology review
Environmental and chemical toxicities: Pathology review
Esophageal disorders: Pathology review
Fat-soluble vitamin deficiency and toxicity: Pathology review
Gallbladder disorders: Pathology review
Gastrointestinal bleeding: Pathology review
GERD, peptic ulcers, gastritis, and stomach cancer: Pathology review
Inflammatory bowel disease: Pathology review
Jaundice: Pathology review
Malabsorption syndromes: Pathology review
Medication overdoses and toxicities: Pathology review
Neuroendocrine tumors of the gastrointestinal system: Pathology review
Pancreatitis: Pathology review
Viral hepatitis: Pathology review
Water-soluble vitamin deficiency and toxicity: B1-B7: Pathology review
Water-soluble vitamin deficiency and toxicity: B9, B12 and vitamin C: Pathology review
Flashcards
Neuroleptic malignant syndrome
0 of 11 complete
Questions
USMLE® Step 1 style questions USMLE
0 of 1 complete
A 23-year-old man is brought to the emergency department after collapsing at a music festival on a hot summer day. The patient was with friends at an electronic dance show. According to his friends, the patient consumed a powdered drug at the concert. Afterwards, while dancing, he suddenly collapsed and started having tremors in the upper and lower extremities. He has a past medical history of depression, anxiety, and bipolar disorder, for which he takes fluoxetine, alprazolam as needed, and aripiprazole. Temperature is 39.0°C (102.2 °F), pulse is 132/min, respirations are 24/min, blood pressure is 172/85 mmHg, and O2 saturation is 97% on room air. On physical examination the patient is diaphoretic, mumbling incoherent sounds, and will not lie still in the gurney. The patient has increased muscle tone. Brief, sudden jerks are present throughout the upper and lower extremities. Which of the following clinical features is most specific to this patient's clinical presentation?
Key Takeaways
Neuroleptic malignant syndrome is a life-threatening neurological disorder most often caused by an adverse reaction to neuroleptic or antipsychotic drugs, which are used to treat mental health conditions, such as schizophrenia, bipolar disorder, and severe depression. Neuroleptic malignant syndrome typically presents with muscle rigidity, fever, autonomic instability, and cognitive changes such as delirium.